Regarding impermanence

I'm not a Buddhist, but some of its assertions come close to those of modern science. In an earlier post, I remarked about its view about the rarity of human life. Another Buddhist tradition, this one from the Tibetans, is the sand mandala. After days of painstaking creation, the work is destroyed in an instant. One panel in the mandala video below is empty; is that a recognition of our imperfection?